The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
備考Best use within three months from the date of receipt of this protein.
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Frizzled family member 11
Smoothened frizzled family receptor
Smoothened homolog (Drosophila)
Smoothened homolog precursor (SMO) (Gx protein)
Smoothened seven transmembrane spanning receptor
機能G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
配列類似性Belongs to the G-protein coupled receptor Fz/Smo family. Contains 1 FZ (frizzled) domain.