Recombinant Human SMARCA6 protein (ab114875)

製品の概要

  • 製品名
    Recombinant Human SMARCA6 protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKI DEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDF NFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVI IYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKR KLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREK VISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF
    • 分子量
      64 kDa including tags
    • 領域
      1 to 348

特性

Our Abpromise guarantee covers the use of ab114875 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • FLJ10339
    • Helicase lymphoid specific
    • Hells
    • HELLS_HUMAN
    • LSH
    • Lymphoid specific helicase
    • Lymphoid-specific helicase
    • Nbla10143
    • PASG
    • Proliferation associated SNF2 like protein
    • Proliferation-associated SNF2-like protein
    • SWI/SNF2 related matrix associated actin dependent regulator of chromatin subfamily A member 6
    • SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6
    see all
  • 機能
    Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis.
  • 組織特異性
    Highly expressed in proliferative tissues such as adult thymus and testis, and expressed at lower levels in uterus, small intestine, colon, and peripheral blood mononuclear cells. Also expressed in neoplastic cell lines including those derived from myeloid and lymphoid leukemias.
  • 配列類似性
    Belongs to the SNF2/RAD54 helicase family.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
  • 細胞内局在
    Nucleus. Closely associated with pericentric heterochromatin.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE showing ab114875 at approximately 64.39kDa.
    Stained with Coomassie Blue.

参考文献

ab114875 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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