製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      KDHSGSESPISDEEERLQSKLSDPHAIEAEKFQCNLCNKTYSTFSGLAKH KQLHCDAQSRKSFSCKYCDKEYV
    • 分子量
      34 kDa including tags
    • 領域
      97 to 169

特性

Our Abpromise guarantee covers the use of ab114212 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Western blot

    ELISA

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • MGC10182
    • Neural crest transcription factor Slug
    • Protein snail homolog 2
    • Slug (chicken homolog) zinc finger protein
    • Slug homolog zinc finger protein
    • Slug zinc finger protein
    • SLUGH
    • SLUGH 1
    • SLUGH1
    • SNAI 2
    • Snai2
    • SNAI2_HUMAN
    • Snail 2
    • Snail homolog 2
    • Snail2
    • WS 2D
    • WS2D
    • Zinc finger protein SLUG
    • Zinc finger protein SNAI2
    see all
  • 機能
    Transcriptional repressor. Involved in the generation and migration of neural crest cells.
  • 組織特異性
    Expressed in placenta and adult heart, pancreas, liver, kidney and skeletal muscle.
  • 関連疾患
    Defects in SNAI2 are the cause of Waardenburg syndrome type 2D (WS2D) [MIM:608890]. WS2 is a genetically heterogeneous, autosomal dominant disorder characterized by sensorineural deafness, pigmentary disturbances, and absence of dystopia canthorum. The frequency of deafness is higher in WS2 than in WS1.
  • 配列類似性
    Belongs to the snail C2H2-type zinc-finger protein family.
    Contains 5 C2H2-type zinc fingers.
  • 細胞内局在
    Nucleus.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE analysis of ab114212 stained with Coomassie Blue.

参考文献

ab114212 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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