製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P63208-2
    • 生物種Human
    • 配列MPSIKLQSSD GEIFEVDVEI AKQSVTIKTM LEDLGMDDEG DDDPVPLPNV NAAILKKVIQ WCTHHKDDPP PPEDDENKEK RTDDIPVWDQ EFLKVDQGTL FELILAANYL DIKGLLDVTC KTVANMIKGK TPEEIRKTFN IKNDFTEEEE AQVGSTQFCL
    • 分子量18 kDa
    • 領域1 to 160

関連製品

特性

Our Abpromise guarantee covers the use of ab117211 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    HPLC

    SDS-PAGE

  • 精製度> 90 % SDS-PAGE.
    ab117211 was purified by proprietary chromatographic techniques and filter sterilized. Greater than 90.0% as determined by RP-HPLC and SDS-PAGE.
  • 製品の状態Liquid
  • 備考Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.29% Sodium chloride, 10% Glycerol

関連情報

  • 別名
    • Cyclin A/CDK2 associated p19
    • Cyclin A/CDK2 associated protein p19
    • Cyclin-A/CDK2-associated protein p19
    • EMC19
    • MGC34403
    • OCP 2
    • OCP II
    • OCP II protein
    • OCP-2
    • OCP-II
    • OCP2
    • OCPII
    • Organ of Corti protein 2
    • Organ of Corti protein II
    • OTTHUMP00000159379
    • OTTHUMP00000159380
    • OTTHUMP00000228275
    • OTTHUMP00000228276
    • OTTHUMP00000228278
    • OTTHUMP00000228279
    • OTTHUMP00000228281
    • p19A
    • p19skp1
    • RNA polymerase II elongation factor like protein
    • RNA polymerase II elongation factor like protein OCP2
    • RNA polymerase II elongation factor-like protein
    • S phase kinase associated protein 1
    • S phase kinase associated protein 1A
    • S phase kinase associated protein 1A p19A
    • S-phase kinase-associated protein 1
    • SIII
    • Skp 1
    • SKP 1A
    • skp1
    • SKP1_HUMAN
    • SKP1A
    • TCEB1L
    • Transcription elongation factor B
    • Transcription Elongation Factor B 1 like
    • Transcription elongation factor B SIII polypeptide 1 like
    see all
  • 機能Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110.
  • パスウェイProtein modification; protein ubiquitination.
  • 配列類似性Belongs to the SKP1 family.
  • Information by UniProt

Recombinant Human Skp1 protein (ab117211) 使用論文

ab117211 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"