Recombinant Human SIGIRR protein (ab108572)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来HEK 293 cells
  • アミノ酸配列
    • アクセッション番号Q6IA17
    • 生物種Human
    • 分子量50 kDa including tags
    • 領域1 to 118

特性

Our Abpromise guarantee covers the use of ab108572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • エンドトキシン・レベル< 0.100 Eu/µg
  • 精製度> 90 % SDS-PAGE.
    ab108572 is 0.2µm filtered
  • 製品の状態Liquid
  • 備考Working aliquots are stable for up to 3 months when stored at -20°C.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS

関連情報

  • 別名
    • Ig IL1 related receptor
    • MGC110992
    • SIGIR_HUMAN
    • SIGIRR
    • Single Ig IL 1 related receptor
    • Single Ig IL-1-related receptor
    • Single Ig IL-1R-related molecule
    • Single Ig IL1R Related Molecule
    • Single immunoglobulin and toll interleukin 1 receptor (TIR) domain
    • Single immunoglobulin and toll interleukin 1 receptor domain
    • Single immunoglobulin domain containing IL1R related protein
    • Single immunoglobulin domain IL1R1 related
    • Single immunoglobulin domain-containing IL1R-related protein
    • TIR 8
    • TIR8
    • Toll/interleukin 1 receptor 8
    • Toll/interleukin-1 receptor 8
    see all
  • 機能Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
  • 組織特異性Mainly expressed in epithelial tissues such as kidney, lung and gut.
  • 配列類似性Belongs to the interleukin-1 receptor family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 TIR domain.
  • 細胞内局在Membrane.
  • Information by UniProt

Recombinant Human SIGIRR protein (ab108572) 使用論文

ab108572 has not yet been referenced specifically in any publications.

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