製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      GLFDKYLGAATSLTVSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWP
    • 分子量
      31 kDa including tags
    • 領域
      228 to 277

関連製品

特性

Our Abpromise guarantee covers the use of ab114508 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • Low affinity sodium glucose cotransporter
    • Low affinity sodium-glucose cotransporter
    • Na(+) glucose cotransporter 2
    • Na(+)/glucose cotransporter 2
    • OTTHUMP00000163298
    • SC5A2_HUMAN
    • SGLT 2
    • SLC5A 2
    • SLC5A2
    • Sodium glucose cotransporter 2
    • Sodium/glucose cotransporter 2
    • Solute carrier family 5 (sodium glucose cotransporter) member 2
    • Solute carrier family 5 (sodium/glucose transporter), member 2
    • Solute carrier family 5 member 2
    see all
  • 機能
    Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1.
    Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
  • 関連疾患
    Defects in SLC5A2 are the cause of renal glucosuria (GLYS1) [MIM:233100]. GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test.
  • 配列類似性
    Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  • 細胞内局在
    Membrane.
  • Information by UniProt

画像

  • ab114508 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

参考文献

ab114508 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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