Recombinant Human Seryl-tRNA synthetase protein (ab116194)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMGSMVLDLDLFRVDKGGDPALIRETQEKRF KDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGDD ESVPENVLSFDDLTADALANLKVSQIKKVRLLIDEAILKCDAERIKLEAE RFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTVRKKYSHVDLVVMV DGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPF FMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIA ALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQF VYSSPHDNKSWEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKL DLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLN ATMCATTRTICAILENYQTEKGITVPEKLKEFMPPGLQELIPFVKPAPIE QEPSKKQKKQHEGSKKKAAARDVTLENRLQNMEVTDA
    • 分子量
      61 kDa including tags
    • 領域
      1 to 514
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab116194 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.
    ab116194 was purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.02% DTT, 10% Glycerol, 0.58% Sodium chloride

関連情報

  • 別名
    • C78314
    • cytoplasmic
    • EC 6.1.1.11
    • FLJ36399
    • sarS
    • Sars1
    • Serine tRNA ligase
    • Serine tRNA ligase 1, cytoplasmic
    • Serine--tRNA ligase
    • serine--tRNA ligase, cytoplasmic
    • SerRS
    • SERS
    • Seryl tRNA Ser/Sec synthetase
    • Seryl tRNA synthetase
    • Seryl tRNA synthetase cytoplasmic
    • Seryl-tRNA Ser/Sec synthetase
    • Seryl-tRNA synthetase
    • seryl-tRNA synthetase, cytoplasmic
    • Seryl-tRNA(Ser/Sec) synthetase
    • Strs
    • SYSC_HUMAN
    see all
  • 機能
    Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
  • パスウェイ
    Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.
  • 配列類似性
    Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
  • ドメイン
    Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
  • 翻訳後修飾
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

画像

  • 15% SDS-PAGE showing ab116194 at approximately 61.2kDa (3µg).

参考文献

ab116194 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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