Recombinant human Serum Amyloid A protein (ab50232)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS NARENIQRFF GRGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY
    • 分子量
      12 kDa
    • 修飾
      unmodified N60 + R71

特性

Our Abpromise guarantee covers the use of ab50232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性

    Tested by its ability to down- regulate lipid biosynthesis in aortic smooth muscle cells. The effective concentration was found to be 4 μM. Schreiber, BM. et al. Biochem J. 1999 Nov 15; 344 Pt 1:7-13

  • アプリケーション

    SDS-PAGE

    Functional Studies

    Western blot

  • エンドトキシン・レベル
    < 0.100 Eu/µg
  • 精製度
    > 98 % SDS-PAGE.
    Greater than 98% by SDS-PAGE and HPLC analyses.
  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成
    Please reconstitute this product in water to a concentration of 1mg/ml.

関連情報

  • 別名
    • Amyloid fibril protein AA
    • Amyloid fibrils
    • Amyloid protein A
    • Fibrils
    • MGC111216
    • OC
    • PIG 4
    • PIG4
    • SAA
    • SAA 1
    • SAA 2
    • SAA_HUMAN
    • SAA1
    • SAA2
    • Serum amyloid A protein precursor
    • Serum amyloid A1 isoform 1
    • Serum amyloid A1 isoform 2
    • Serum amyloid protein A(4-101)
    • TP53I4
    • Tumor protein p53 inducible protein 4
    see all
  • 機能
    Major acute phase reactant. Apolipoprotein of the HDL complex.
  • 組織特異性
    Expressed by the liver; secreted in plasma.
  • 関連疾患
    Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
    Note=Elevated serum SSA protein levels may be associated with lung cancer.
  • 配列類似性
    Belongs to the SAA family.
  • 翻訳後修飾
    This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

ab50232 has not yet been referenced specifically in any publications.

レビューと Q&A

Thank you for your patience in this matter. I have verified that ab50232 (Serum Amyloid A protein (Active)) does not contain sodium azide or any other added preservatives. Please do not hesitate to contact us again if you have any further quest...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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