This product is an active protein and may elicit a biological response in vivo, handle with caution.
C type lectin domain family 11 member A
C type lectin superfamily member 3
C-type lectin domain family 11 member A
C-type lectin superfamily member 3
Lymphocyte secreted C type lectin
Lymphocyte secreted C-type lectin
Stem cell growth factor
機能Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.
組織特異性Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.
配列類似性Contains 1 C-type lectin domain.
発生段階In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils.
翻訳後修飾O-glycosylated. Probably sulfated on the O-glycans.