Recombinant Human SCGF beta protein (ab54178)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Human

関連製品

特性

Our Abpromise guarantee covers the use of ab54178 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 95 % SDS-PAGE.
    Purity: 98 % (SDS-PAGE, HPLC) Endotoxin level: < 0.1 ng per ug of SCGF beta
  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 0.5 x PBS, pH 7.3

  • 再構成
    The lyophilized SCGF beta is soluble in water and most aqueous buffers. The lyophilized protein should be reconstituted in water to a concentration of 0.1 - 1.0 mg/ml. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.

関連情報

  • 別名
    • C type lectin domain family 11 member A
    • C type lectin superfamily member 3
    • C-type lectin domain family 11 member A
    • C-type lectin superfamily member 3
    • CLC11_HUMAN
    • CLEC11A
    • CLECSF3
    • LSLCL
    • Lymphocyte secreted C type lectin
    • Lymphocyte secreted C-type lectin
    • p47
    • Stem cell growth factor
    see all
  • 機能
    Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.
  • 組織特異性
    Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.
  • 配列類似性
    Contains 1 C-type lectin domain.
  • 発生段階
    In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils.
  • 翻訳後修飾
    O-glycosylated. Probably sulfated on the O-glycans.
  • 細胞内局在
    Cytoplasm. Secreted.
  • Information by UniProt

参考文献

ab54178 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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