製品の概要

  • 製品名Recombinant Human SAFB protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号Q15424
    • 生物種Human
    • 配列DGQEDVETSLENLQDIDIMDISVLDEAEIDNGSVADCVEDDDADNLQESL SDSRELVEGEMKELPEQLQEHAIEDKETINNLDTSSSDFT
    • 分子量36 kDa including tags
    • 領域111 to 200

特性

Our Abpromise guarantee covers the use of ab116906 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • DKFZp779C1727
    • glutathione S transferase fusion protein
    • HAP
    • HET
    • HSP27 ERE TATA binding protein
    • HSP27 ERE-TATA-binding protein
    • HSP27 estrogen response element-TATA box-binding protein
    • SAF B
    • SAF-B
    • SAF-B1
    • SAFB
    • SAFB 1
    • SAFB1
    • SAFB1_HUMAN
    • Scaffold attachment factor B1
    see all
  • 機能Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. Can inhibit cell proliferation.
  • 組織特異性Ubiquitous. Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.
  • 配列類似性Contains 1 RRM (RNA recognition motif) domain.
    Contains 1 SAP domain.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human SAFB protein 画像

  • 12.5% SDS-PAGE stained with Coomassie Blue showing ab116906 at approximately 35.53 kDa.

Recombinant Human SAFB protein (ab116906) 使用論文

ab116906 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"