May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
Belongs to the S-100 family. Contains 2 EF-hand domains.
15% SDS-PAGE showing ab104645 at approximately 12.3kDa (3µg).
This product has been referenced in:
Lorenzi R et al. Soluble form of receptor for advanced glycation end-products (sRAGE): do sRAGE ligands or anti-sRAGE auto-antibodies interfere with sRAGE quantification? Ann Clin BiochemN/A:N/A (2013).
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