製品の概要

  • 製品名
    Recombinant Human RUNX3 protein
  • タンパク質長
    Protein fragment

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHH SSGLVPRGSH MRSMVDVLAD HAGELVRTDS PNFLCSVLPS HWRCNKTLPV AFKVVALGDV PDGTVVTVMA GNDENYSAEL RNASAVMKNQ VARFNDLRFV GRSGRGKSFT LTITVFTNPT QVATYHRAIK VTVDGPREPR RHRQK
    • 分子量
      17 kDa including tags
    • 領域
      53 to 186
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab95893 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF-TOF
  • 精製度
    > 95 % SDS-PAGE.
    ab95893 is purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

関連情報

  • 別名
    • Acute myeloid leukemia 2 protein
    • Acute myeloid leukemia gene 2
    • AML 2
    • AML2
    • CBF alpha 3
    • CBF-alpha-3
    • CBFA 3
    • CBFA3
    • core binding factor
    • Core binding factor alpha 3 subunit
    • Core binding factor runt domain alpha subunit 3
    • Core binding factor subunit alpha 3
    • core-binding factor
    • Core-binding factor subunit alpha-3
    • Oncogene AML 2
    • Oncogene AML-2
    • PEA2 alpha C
    • PEA2-alpha C
    • PEBP2 alpha C
    • PEBP2-alpha C
    • Pebp2a3
    • PEBP2aC
    • Polyomavirus enhancer binding protein 2 alpha C subunit
    • Polyomavirus enhancer-binding protein 2 alpha C subunit
    • runt domain alpha subunit 3
    • runt related transcription factor 3
    • Runt-related transcription factor 3
    • RUNX 3
    • Runx3
    • RUNX3_HUMAN
    • SL3 3 enhancer factor 1 alpha C subunit
    • SL3-3 enhancer factor 1 alpha C subunit
    • SL3/AKV core binding factor alpha C subunit
    • SL3/AKV core-binding factor alpha C subunit
    • Transcription factor AML2
    see all
  • 機能
    CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters.
  • 配列類似性
    Contains 1 Runt domain.
  • ドメイン
    A proline/serine/threonine rich region at the C-terminus is necessary for transcriptional activation of target genes.
  • 翻訳後修飾
    Phosphorylated on tyrosine residues by SRC. Phosphorylated by LCK and FYN.
  • 細胞内局在
    Nucleus. Cytoplasm. The tyrosine phosphorylated form localizes to the cytoplasm.
  • Information by UniProt

画像

  • 15% SDS-PAGE showing ab95893 at approximately 17.1kDa (3µg).

参考文献

ab95893 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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