製品の概要

  • 製品名
    Recombinant Human RRM2 protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHH SSGLVPRGSH MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDEPLLRENPRRF VIFPIEYHDI WQMYKKAEAS FWTAEEVDLS KDIQHWESLK PEERYFISHV LAFFAASDGI VNENLVERFS QEVQITEARC FYGFQIAMEN IHSEMYSLLI DTYIKDPKER EFLFNAIETM PCVKKKADWA LRWIGDKEAT YGERVVAFAA VEGIFFSGSF ASIFWLKKRGLMPGLTFSNE LISRDEGLHC DFACLMFKHL VHKPSEERVR EIIINAVRIE QEFLTEALPV KLIGMNCTLM KQYIEFVADR LMLELGFSKV FRVENPFDFM ENISLEGKTN FFEKRVGEYQ RMGVMSSPTE NSFTLDADF
    • 分子量
      47 kDa including tags
    • 領域
      1 to 389
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab99137 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    >= 85 % SDS-PAGE.
    ab99137 was purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8

関連情報

  • 別名
    • cb111
    • chunp6884
    • etID309896.20
    • R2
    • reductase M2 polypeptide variant 1
    • reductase M2 polypeptide variant 2
    • reductase M2 polypeptide variant 3a
    • reductase M2 polypeptide variant 3b
    • reductase M2 polypeptide variant 3c
    • reductase M2 polypeptide variant 3d
    • Ribonucleoside-diphosphate reductase subunit M2
    • Ribonucleotide reductase M2
    • Ribonucleotide reductase M2 polypeptide
    • Ribonucleotide reductase M2 subunit
    • ribonucleotide reductase protein r2 class I
    • Ribonucleotide reductase regulatory subunit M2
    • Ribonucleotide reductase small chain
    • Ribonucleotide reductase small subunit
    • Ribonucleotide reductase, R2 subunit
    • RIR2_HUMAN
    • RR2
    • RR2M
    • RRM2
    see all
  • 機能
    Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
  • パスウェイ
    Genetic information processing; DNA replication.
  • 配列類似性
    Belongs to the ribonucleoside diphosphate reductase small chain family.
  • 翻訳後修飾
    Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

画像

  • 15% SDS-PAGE analysis of ab99137 (3ug)

参考文献

ab99137 has not yet been referenced specifically in any publications.

レビューと Q&A

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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