Recombinant Human Ribosomal protein S10 (ab116863)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P46783
    • 生物種Human
    • 配列MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQ SLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRRSRPE TGKPRPKGLEGERPARLTRGEADRDTYRRSAVPPGADKKAEAGAGSATEF QFRGGFGRGRGQPPQ
    • 分子量44 kDa including tags
    • 領域1 to 165

関連製品

特性

Our Abpromise guarantee covers the use of ab116863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • 40S ribosomal protein S10
    • DBA9
    • MGC88819
    • OTTHUMP00000016229
    • OTTHUMP00000016230
    • RPS10
    • RS10_HUMAN
    • S10
    see all
  • 機能Component of the 40S ribosomal subunit.
  • 関連疾患Defects in RPS10 are the cause of Diamond-Blackfan anemia type 9 (DBA9) [MIM:613308]. It is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre- Robin syndrome and cleft palate), thumb and urogenital anomalies.
  • 配列類似性Belongs to the ribosomal protein S10e family.
  • 翻訳後修飾Methylated by PRMT5. Methylation is necessary for its interaction with NPS1, its localization in the granular component (GC) region of the nucleolus, for the proper assembly of ribosomes, protein synthesis and optimal cell proliferation.
  • 細胞内局在Cytoplasm. Nucleus > nucleolus. Localized in the granular component (GC) region of the nucleolus. Methylation is required for its localization in the GC region. Co-localizes with NPS1 in the GC region of the nucleolus.
  • Information by UniProt

Recombinant Human Ribosomal protein S10 画像

  • 12.5% SDS-PAGE stained with Coomassie Blue showing ab116863 at approximately 43.89 kDa.

Recombinant Human Ribosomal protein S10 (ab116863) 使用論文

ab116863 has not yet been referenced specifically in any publications.

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