製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Human

特性

Our Abpromise guarantee covers the use of ab91341 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 95 % SDS-PAGE.

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50% Glycerol, 5mM Magnesium chloride, 25mM HEPES, 0.01mM GDP, pH 7.4

関連情報

  • 別名
    • Ras homolog enriched in brain 2, formerly
    • GTP binding protein Rheb
    • GTP-binding protein Rheb
    • MGC111559
    • Ras homolog enriched in brain
    • Ras homolog enriched in brain 2
    • Rheb
    • RHEB 2
    • RHEB_HUMAN
    • RHEB2
    • RHEB2, formerly
    see all
  • 機能
    Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.
  • 組織特異性
    Ubiquitous. Highest levels observed in skeletal and cardiac muscle.
  • 配列類似性
    Belongs to the small GTPase superfamily. Rheb family.
  • 翻訳後修飾
    Farnesylation is important for efficiently activating mTORC1-mediated signaling.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt

画像

  • SDS-PAGE showing ab91341 at 47 kDa

参考文献

ab91341 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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