製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHH SSGLVPRGSH MQSAMFLAVQ HDCRPMDKSA GSGHKSEEKR EKMKRTLLKD WKTRLSYFLQ NSSTPGKPKT GKKSKQQAFI KPSPEEAQLW SEAFDELLAS KYGLAAFRAF LKSEFCEENI EFWLACEDFK KTKSPQKLSS KARKIYTDFI EKEAPKEINI DFQTKTLIAQ NIQEATSGCF TTAQKRVYSL MENNSYPRFL ESEFYQDLCK KPQITTEPHA T
    • 分子量
      27 kDa including tags
    • 領域
      1 to 211
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab125783 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.
    ab125783 is purified by proprietary chromatographic techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.03% DTT, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

関連情報

  • 別名
    • Basic helix-loop-helix phosphoprotein G0S8
    • Cell growth inhibiting protein 31
    • Cell growth-inhibiting gene 31 protein
    • G0 to G1 switch regulatory 8 24kD
    • G0/G1 switch regulatory protein 8
    • G0S8
    • GOS8
    • OTTHUMP00000060765
    • Regulator of G protein signaling 2
    • Regulator of G protein signalling 2 24kD
    • Regulator of G-protein signaling 2
    • Regulators of G protein signaling XRGSVI
    • RGS 2
    • RGS2
    • RGS2_HUMAN
    see all
  • 機能
    Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320).
  • 組織特異性
    Expressed in acute myelogenous leukemia (AML) and in acute lymphoblastic leukemia (ALL).
  • 配列類似性
    Contains 1 RGS domain.
  • 翻訳後修飾
    Phosphorylated by protein kinase C. Phosphorylation by PRKG1 leads to activation of RGS2 activity.
  • 細胞内局在
    Cell membrane. Mitochondrion and Cell membrane. Cytoplasm. Nucleus, nucleolus.
  • Information by UniProt

Recombinant Human RGS2 protein (ab125783) 使用論文

ab125783 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125783.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録