製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号O15492
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MCRTLAAFPT TCLERAKEFK TRLGIFLHKS ELGCDTGSTG KFEWGSKHSK ENRNFSEDVL GWRESFDLLL SSKNGVAAFH AFLKTEFSEE NLEFWLACEE FKKIRSATKL ASRAHQIFEE FICSEAPKEV NIDHETRELT RMNLQTATAT CFDAAQGKTR TLMEKDSYPR FLKSPAYRDL AAQASAASAT LSSCSLDEPS HT
    • 分子量25 kDa including tags
    • 領域1 to 202
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab116421 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 90 % SDS-PAGE.
    Purified by proprietary chromatographic techniques.
  • 製品の状態Liquid
  • 備考ab116421 although stable at 4°C for 30 days, should be stored desiccated below -20°C for periods greater than 30 days. Please avoid freeze-thaw cycles.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.32% Tris-HCl buffer, 0.58% Sodium chloride, 20% Glycerol

関連情報

  • 別名
    • A28 RGS14
    • A28 RGS14P
    • A28-RGS14P
    • HGNC:9997
    • hRGS-r
    • OTTHUMP00000033147
    • Regulator of G protein signaling 16
    • Regulator of G protein signalling 16
    • Regulator of G-protein signaling 16
    • Retinal-specific RGS
    • Retinally abundant regulator of G protein signaling
    • Retinally abundant regulator of G-protein signaling
    • RGS 16
    • RGS R
    • RGS-R
    • Rgs14
    • RGS16
    • RGS16_HUMAN
    • RGSR
    see all
  • 機能Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade.
  • 組織特異性Abundantly expressed in retina with lower levels of expression in most other tissues.
  • 配列類似性Contains 1 RGS domain.
  • 翻訳後修飾Palmitoylated on Cys-2 and/or Cys-12.
    Phosphorylation on Tyr-168 upon EGFR stimulation. Enhanced GTPase accelerating (GAP) activity on G(i)-alpha.
  • Information by UniProt

Recombinant Human RGS16 protein (ab116421) 使用論文

ab116421 has not yet been referenced specifically in any publications.

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