製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Human
    • 領域
      14 to 209

特性

Our Abpromise guarantee covers the use of ab89814 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: 150mM Imidazole
    Constituents: 25% Glycerol, 50mM Sodium phosphate, 300mM Sodium chloride, 2mM DTT, 0.1mM PMSF, pH 7.0

関連情報

  • 別名
    • 1R20
    • B cell activation protein BL34
    • B-cell activation protein BL34
    • BL34
    • Early response protein 1R20
    • IER 1
    • IER1
    • Immediate early response 1 B cell specific
    • immediate-early response 1, B-cell specific
    • IR20
    • Regulator of G protein signalling 1
    • Regulator of G-protein signaling 1
    • RGS 1
    • RGS1
    • RGS1_HUMAN
    see all
  • 機能
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation.
  • 組織特異性
    B-cell specific. Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin lymphoma and hairy cell leukemia, expression is constitutively high.
  • 配列類似性
    Contains 1 RGS domain.
  • 翻訳後修飾
    Could be phosphorylated. Might be functionally regulated by protein kinase(s).
  • Information by UniProt

画像

  • SDS-PAGE showing ab89814 at approximately 26kDa.

参考文献

ab89814 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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