Recombinant Human Retinoic Acid Receptor beta protein (ab81841)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human

特性

Our Abpromise guarantee covers the use of ab81841 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    ab81841 was expressed in a bacterial system and purified by an affinity column in combination with FPLC chromatography it showed greater than 95% homogeneous and contains no detectable protease, DNase and RNase activity.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8

関連情報

  • 別名
    • HAP
    • HBV-activated protein
    • NR1B2
    • Nuclear receptor subfamily 1 group B member 2
    • RAR B
    • RAR beta
    • RAR epsilon
    • RAR-beta
    • RAR-epsilon
    • RARB
    • RARB_HUMAN
    • Retinoic acid receptor beta
    • Retinoic acid receptor beta 2
    • Retinoic acid receptor beta 4
    • Retinoic acid receptor beta 5
    • Retinoic acid receptor beta polypeptide
    • RRB2
    see all
  • 機能Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
  • 関連疾患Microphthalmia, syndromic, 12
  • 配列類似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • ドメインComposed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • 細胞内局在Cytoplasm and Nucleus.
  • Information by UniProt

Recombinant Human Retinoic Acid Receptor beta protein (ab81841) 使用論文

ab81841 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"