製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMAKSAEVKLAIFGRAGVGKSALVVRFLTKR FIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQEDTIQREGHMRWGEGF VLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDHSRQVST EEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRMVQGKTRRR SSTTHVKQAINKMLTKISS
    • 分子量
      25 kDa including tags
    • 領域
      1 to 199
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab124982 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 85 % SDS-PAGE.
    ab124982 is purified by proprietary chromatographic techniques and is sterile filtered. Purity is greater than 85.0% as determined by SDS-PAGE.
  • 製品の状態
    Liquid
  • 備考
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

    pH: 8.00
    Constituents: 0.08% DTT, 0.32% Tris HCl, 50% Glycerol, 1.17% Sodium chloride

関連情報

  • 別名
    • MGC15754
    • RAS like estrogen regulated growth inhibitor
    • Ras related and estrogen regulated growth inhibitor
    • Ras-related and estrogen-regulated growth inhibitor
    • Rerg
    • RERG_HUMAN
    • Weakly similar to N ras protein [H.sapiens]
    see all
  • 機能
    Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.
  • 組織特異性
    Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor-positive breast-derived cell lines, but not in estrogen receptor-negative cell lines. Expression is decreased or lost in a significant proportion of primary breast tumors with poor clinical prognosis.
  • 配列類似性
    Belongs to the small GTPase superfamily. Ras family.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

参考文献

ab124982 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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