The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
備考Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
arginine glutamic acid dipeptide (RE) repeats
arginine glutamic acid dipeptide repeats
Arginine glutamic acid dipeptide repeats protein
Arginine-glutamic acid dipeptide repeats protein
ARGININE-GLUTAMIC ACID REPEATS-ENCODING GENE
atrophin 1 like
Atrophin 1 like protein
Atrophin 1 related protein
atrophin related protein
機能Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.
組織特異性Widely expressed. Expressed in tumor cell lines.
関連疾患Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line. Translocation t(1;15)(p36.2;q24).