Recombinant Human Radixin protein (ab114380)

製品の概要

  • 製品名Recombinant Human Radixin protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P35241
    • 生物種Human
    • 配列MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYV DSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQR LFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLAND RLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEM YGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISF NDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI EVQQMKAQAREEKHQKQLERAQLENEKEKREIAEKEKERIEREKEELMER LKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAK SAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAF AAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAEL SNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVL HAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM
    • 分子量90 kDa including tags
    • 領域1 to 583

特性

Our Abpromise guarantee covers the use of ab114380 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    ab114380 is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

関連情報

  • 別名
    • CB567
    • CG12537
    • DFNB24
    • ESP10
    • Hh-induced MATH and BTB domain-containing protein
    • HIB
    • Moesin-B
    • Protein roadkill
    • RADI_HUMAN
    • Radixin
    • RDX
    see all
  • 機能Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.
  • 関連疾患Defects in RDX are the cause of deafness autosomal recessive type 24 (DFNB24) [MIM:611022]. DFNB24 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
  • 配列類似性Contains 1 FERM domain.
  • ドメインThe N-terminal domain interacts with the C-terminal domain of LAYN. An interdomain interaction between its N-terminal and C-terminal domains inhibits its ablilty to bind LAYN. In the presence of acidic phospholipids, the interdomain interaction is inhibited and this enhances binding to LAYN.
  • 翻訳後修飾Phosphorylated by tyrosine-protein kinases.
  • 細胞内局在Cell membrane. Cytoplasm > cytoskeleton. Cleavage furrow. Highly concentrated in the undercoat of the cell-to-cell adherens junction and the cleavage furrow in the interphase and mitotic phase, respectively.
  • Information by UniProt

Recombinant Human Radixin protein 画像

  • ab114380 analysed on a 12.5% SDS-PAGE Stained with Coomassie Blue.

Recombinant Human Radixin protein (ab114380) 使用論文

ab114380 has not yet been referenced specifically in any publications.

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