製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MSTPARRRLM RDFKRLQEDP PAGVSGAPSE NNIMVWNAVI FGPEGTPFED GTFKLTIEFT EEYPNKPPTVRFVSKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ SLLDEPNPNS PANSQAAQLY QENKREYEKR VSAIVEQSWR DC

特性

Our Abpromise guarantee covers the use of ab95493 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

    Immunohistochemistry methylmethacrylate sections

  • 質量分析
    MALDI-TOF-TOF
  • 精製度> 95 % SDS-PAGE.
    Purified by using conventional chromatography techniques
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 1mM EDTA, 1mM DTT, pH 8

関連情報

  • 別名
    • BHR6A
    • hHR6A
    • HR6A
    • mHR6A
    • MRXS30
    • MRXSN
    • RAD6 homolog A
    • RAD6A
    • UBC2
    • UBCD6
    • UBE2A
    • Ube2a ubiquitin-conjugating enzyme E2A
    • UBE2A_HUMAN
    • Ubiquitin carrier protein
    • Ubiquitin carrier protein A
    • Ubiquitin conjugating enzyme E2 17 kDa
    • Ubiquitin conjugating enzyme E2 21.5 kDa
    • Ubiquitin conjugating enzyme E2A
    • Ubiquitin conjugating enzyme E2A (RAD6 homolog)
    • Ubiquitin protein ligase A
    • Ubiquitin-conjugating enzyme E2 A
    • Ubiquitin-protein ligase A
    see all
  • 機能Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.
  • パスウェイProtein modification; protein ubiquitination.
  • 配列類似性Belongs to the ubiquitin-conjugating enzyme family.
  • Information by UniProt

Recombinant Human Rad6 protein 画像

  • 15% SDS-PAGE analysis of ab95493 (3ug)

Recombinant Human Rad6 protein (ab95493) 使用論文

ab95493 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"