製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P61006
    • 生物種Human
    • 配列MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTI ELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIR NWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMET SAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSNQGVKITPDQQKRSS FFRCVLL
    • 分子量49 kDa including tags
    • 領域1 to 207

特性

Our Abpromise guarantee covers the use of ab116785 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

    ELISA

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • AA409338
    • MEL
    • Mel transforming oncogene
    • Mel transforming oncogene (derived from cell line NK14)
    • Mel transforming oncogene (derived from cell line NK14) RAB8 homolog
    • Mel transforming oncogene (RAB8 homolog)
    • MGC124948
    • Oncogene c mel
    • Oncogene c-mel
    • RAB8
    • RAB8A
    • RAB8A member RAS oncogene family
    • RAB8A_HUMAN
    • Ras associated protein RAB8
    • Ras related protein Rab 8A
    • Ras-related protein Rab-8A
    see all
  • 機能May be involved in vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization.
  • 配列類似性Belongs to the small GTPase superfamily. Rab family.
  • 細胞内局在Cell membrane. Golgi apparatus. Cytoplasm > perinuclear region. Cell projection. Colocalizes with OPTN at the Golgi complex and in vesicular structures close to the plasma membrane. In the GDP-bound form, present in the perinuclear region. Shows a polarized distribution to distal regions of cell protrusions in the GTP-bound form. Colocalizes with PARD3, PRKCI, EXOC5, OCLN, PODXL and RAB11A in apical membrane initiation sites (AMIS) during the generation of apical surface and luminogenesis.
  • Information by UniProt

Recombinant Human RAB8A protein 画像

  • ab116785 analysed on a 12.5% SDS-PAGE Stained with Coomassie Blue.

Recombinant Human RAB8A protein (ab116785) 使用論文

ab116785 has not yet been referenced specifically in any publications.

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