製品の概要

  • 製品名Recombinant Human RAB35 protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q15286
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMARDYDHLFKLLIIGDSGVGKSSLLLRFAD NTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRG THGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVV ETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQ QQQQNDVVKLTKNSKRKKRCC
    • 分子量25 kDa including tags
    • 領域1 to 201
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab113586 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Mass Spectrometry

    SDS-PAGE

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab113586 was purified using conventional chromatography.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 40% Glycerol, 0.88% Sodium chloride, 0.02% DTT

関連情報

  • 別名
    • GTP binding protein RAY
    • GTP-binding protein RAY
    • H ray
    • OTTHUMP00000240256
    • OTTHUMP00000240257
    • OTTHUMP00000240258
    • OTTHUMP00000240259
    • RAB1C
    • Rab35
    • RAB35 member RAS oncogene family
    • RAB35, member RAS oncogene family
    • RAB35_HUMAN
    • Ras related protein Rab 1C
    • Ras related protein rab 1c (GTP binding protein ray)
    • Ras related protein Rab35
    • Ras-related protein Rab-1C
    • Ras-related protein Rab-35
    • RAY
    see all
  • 機能In the process of endocytosis, essential rate-limiting regulator of a fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge.
  • 配列類似性Belongs to the small GTPase superfamily. Rab family.
  • 細胞内局在Cell membrane. Membrane > clathrin-coated pit. Cytoplasmic vesicle > clathrin-coated vesicle. Endosome. Melanosome. Present on sorting endosomes and endosomal tubules. Tends to be enriched in PIP2-positive cell membrane domains. During mitosis, associated with the plasma membrane and present at the ingressing furrow during early cytokinesis as well as at the intercellular bridge later during cytokinesis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

Recombinant Human RAB35 protein 画像

  • 15% SDS-PAGE analysis of 3 µg ab113586.

Recombinant Human RAB35 protein (ab113586) 使用論文

ab113586 has not yet been referenced specifically in any publications.

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