Recombinant Human PXR protein (ab82046)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 領域138 to 434

特性

Our Abpromise guarantee covers the use of ab82046 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 7.9

関連情報

  • 別名
    • BXR
    • Nr1i2
    • NR1I2_HUMAN
    • Nuclear receptor subfamily 1 group I member 2
    • ONR 1
    • ONR1
    • Orphan nuclear receptor PAR 1
    • Orphan nuclear receptor PAR1
    • Orphan nuclear receptor PXR
    • OTTHUMP00000215173
    • OTTHUMP00000215174
    • OTTHUMP00000215175
    • PAR
    • PAR 1
    • PAR 2
    • PAR q
    • PAR1
    • PAR2
    • PARq
    • pregnane X nuclear receptor variant 2
    • Pregnane X receptor
    • PRR
    • PXR
    • SAR
    • Steroid and xenobiotic receptor
    • SXR
    see all
  • 機能Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.
  • 組織特異性Expressed in liver, colon and small intestine.
  • 配列類似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human PXR protein (ab82046) 使用論文

ab82046 has not yet been referenced specifically in any publications.

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