Recombinant Human Protein phosphatase inhibitor 1 (ab78756)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列MEQDNSPRKI QFTVPLLEPH LDPEAAEQIR RRRPTPATLV LTSDQSSPEI DEDRIPNPHL KSTLAMSPRQ RKKMTRITPT MKELQMMVEH HLGQQQQGEE PEGAAESTGT QESRPPGIPD TEVESRLGTS GTAKKTAECI PKTHERGSKE PSTKEPSTHI PPLDSKGANS VLEHHHHHH

特性

Our Abpromise guarantee covers the use of ab78756 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 90 % SDS-PAGE.
    ab78756 is purified by using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 50mM Tris, 1mM EDTA, 1mM DTT, 0.1mM PMSF, pH 8.0

関連情報

  • 別名
    • I 1
    • I-1
    • I1
    • Inhibitor 1
    • IPP 1
    • IPP-1
    • IPP1
    • Ppp1r1a
    • PPR1A_HUMAN
    • Protein phosphatase 1 regulatory (inhibitor) subunit 1A
    • Protein phosphatase 1 regulatory subunit 1A
    • Protein phosphatase inhibitor 1
    see all
  • 機能Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
  • 配列類似性Belongs to the protein phosphatase inhibitor 1 family.
  • 翻訳後修飾Phosphorylation of Thr-35 is required for activity.
  • Information by UniProt

Recombinant Human Protein phosphatase inhibitor 1 画像

  • 15% SDS-PAGE showing ab78756 at approximately 20kDa (3µg).

Recombinant Human Protein phosphatase inhibitor 1 (ab78756) 使用論文

ab78756 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

I am happy to help you with your inquiry.

Do you want to use these in your lysis buffer and keep the phosphorylation side of your target protein intact? If this is the case I am sorry to confirm that the t...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"