Recombinant Human Prostaglandin D Synthase (hematopoietic) protein (ab88041)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Saccharomyces cerevisiae
  • アミノ酸配列
    • 生物種Human
    • 配列MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGK IPILE VDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDF MSCFPWAEKKQD VKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSV TWADFYWEICSTTLLVFKP DLLDNHPRLVTLRKKVQAIPAVANWIKRR PQTKL

特性

Our Abpromise guarantee covers the use of ab88041 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 30% Glycerol, 0.5% Triton-X-100, 50mM HEPES, 30mM Glutathione, 100mM Sodium chloride, 1mM DTT, pH 7.5

関連情報

  • 別名
    • Cerebrin 28
    • Glutathione dependent PGD synthetase
    • Glutathione S-transferase
    • Glutathione-dependent PGD synthase
    • Glutathione-requiring prostaglandin D synthase
    • GST class-sigma
    • H PGDS
    • H-PGDS
    • Haematopoietic prostaglandin D synthase
    • Haematopoietic prostaglandin D2 synthase
    • Hematopoietic prostaglandin D synthase
    • Hpgds
    • HPGDS_HUMAN
    • Prostaglandin D synthase
    • Prostaglandin D2 synthase hematopoietic
    • Prostaglandin H2 D isomerase
    • Prostaglandin-H2 D-isomerase
    • PTGDS2
    see all
  • 機能Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
  • 組織特異性Expressed in a number of megakaryocytic cell lines but not in platelets. Highly expressed in adipose tissue, macrophages and placenta. Also expressed at lower levels in lung, heart, lymph nodes, appendix, bone marrow and fetal liver.
  • 配列類似性Belongs to the GST superfamily. Sigma family.
    Contains 1 GST C-terminal domain.
    Contains 1 GST N-terminal domain.
  • 発生段階Highest levels in immature megakaryocytic cells. Disappears after final differentiation to platelets.
  • 細胞内局在Cytoplasm.
  • Information by UniProt

Recombinant Human Prostaglandin D Synthase (hematopoietic) protein (ab88041) 使用論文

ab88041 has not yet been referenced specifically in any publications.

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