Recombinant Human Properdin protein (ab114924)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      PHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGP WGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPC PVDGEWDSWGEWSPCIRRNMKS
    • 分子量
      39 kDa including tags
    • 領域
      213 to 334

特性

Our Abpromise guarantee covers the use of ab114924 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

    ELISA

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

関連情報

  • 別名
    • BFD
    • CFP
    • Complement factor P
    • Complement factor properdin
    • Factor P
    • PFC
    • PFD
    • PROP_HUMAN
    • Properdin
    • Properdin P factor complement
    see all
  • 機能
    A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes.
  • 関連疾患
    Defects in CFP are the cause of properdin deficiency (PFD) [MIM:312060]. PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III).
  • 配列類似性
    Contains 6 TSP type-1 domains.
  • 細胞内局在
    Secreted.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE showing ab114924 at approximately 39.05kDa.
    Stained with Coomassie Blue.

参考文献

ab114924 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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