製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列MAGWNAYIDN LMADGTCQDA AIVGYKDSPS VWAAVPGKTF VNITPAEVGV LVGKDRSSFY VNGLTLGGQK CSVIRDSLLQ DGEFSMDLRT KSTGGAPTFN VTVTKTDKTL VLLMGKEGVH GGLINKKCYE MASHLRRSQY

特性

Our Abpromise guarantee covers the use of ab87760 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    ab87760 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • 備考Endotoxin level: < 1.0 EU per 1 µg of protein (determined by LAL method).
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, pH 8.0

関連情報

  • 別名
    • Actin binding protein
    • ALS18
    • Epididymis tissue protein Li 184a
    • OTTHUMP00000125244
    • Pfn
    • PFN 1
    • PFN1
    • PROF1_HUMAN
    • Profilin I
    • Profilin-1
    • Profilin1
    • ProfilinI
    see all
  • 機能Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
  • 配列類似性Belongs to the profilin family.
  • 細胞内局在Cytoplasm > cytoskeleton.
  • Information by UniProt

Recombinant Human Profilin 1 protein 画像

  • 15% SDS-PAGE analysis of 3µg ab87760.

Recombinant Human Profilin 1 protein (ab87760) 使用論文

This product has been referenced in:
  • Zienkiewicz A  et al. Chip-based capillary electrophoresis profiling of olive pollen extracts used for allergy diagnosis and immunotherapy. Electrophoresis 35:2681-5 (2014). Read more (PubMed: 24888349) »
  • Caglayan E  et al. Profilin-1 is expressed in human atherosclerotic plaques and induces atherogenic effects on vascular smooth muscle cells. PLoS One 5:e13608 (2010). Read more (PubMed: 21049052) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"