Recombinant Human PRODH protein (ab114814)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号O43272
    • 生物種Human
    • 配列LVRGAYLAQERARAAEIGYEDPINPTYEATNAMYHRCLDYVLEELKHNAK AKVMVASHNEDTVRFALRRMEELGLHPADHRVYFGQLLGMCDQISFPLGQ
    • 分子量37 kDa including tags
    • 領域441 to 540

特性

Our Abpromise guarantee covers the use of ab114814 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • HSPOX2
    • mitochondrial
    • P53 induced gene 6 protein
    • p53-induced gene 6 protein
    • PIG6
    • POX
    • PROD_HUMAN
    • PRODH
    • PRODH 1
    • PRODH 2
    • PRODH1
    • PRODH2
    • Proline dehydrogenase
    • proline dehydrogenase (oxidase) 1
    • proline dehydrogenase (proline oxidase)
    • Proline dehydrogenase 1
    • Proline dehydrogenase 1, mitochondrial
    • Proline oxidase
    • Proline oxidase 1
    • Proline oxidase 2
    • Proline oxidase, mitochondrial
    • Proline oxidase, mitochondrial precursor
    • SCZD4
    • TP53I6
    • tumor protein p53 inducible protein 6
    see all
  • 機能Converts proline to delta-1-pyrroline-5-carboxylate.
  • 組織特異性Expressed in lung, skeletal muscle and brain, to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas.
  • パスウェイAmino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2.
  • 関連疾患Defects in PRODH are the cause of hyperprolinemia type 1 (HP-1) [MIM:239500]. HP-1 is a disorder characterized by elevated serum proline levels. May be involved in the psychiatric and behavioral phenotypes associated with the 22q11 velocardiofacial and DiGeorge syndrome.
    Defects in PRODH are associated with susceptibility to schizophrenia type 4 (SCZD4) [MIM:600850]. A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder.
  • 配列類似性Belongs to the proline oxidase family.
  • 細胞内局在Mitochondrion matrix.
  • Information by UniProt

Recombinant Human PRODH protein 画像

  • 12.5% SDS-PAGE Stained with Coomassie Blue

Recombinant Human PRODH protein (ab114814) 使用論文

ab114814 has not yet been referenced specifically in any publications.

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The protein has not been tested for its activity so I am sorry we are unable to confirm. The protein should not be expected to be active because it is not a full length protein it is a fragment which was used as a ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"