Recombinant Human proBNP protein (ab51403)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列HPLG SPGSASDLET SGLQEQRNHL QGKLSELQVE QTSLEPLQES PRPTGVWKSR EVATEGIRGH RKMVLYTLRA PR
    • 領域27 to 102
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab51403 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性ab51403 corresponds to the first 76 aa residues after the signal peptide has been cleved.
  • アプリケーション

    Western blot

  • 精製度> 90 % SDS-PAGE.
    ab51403 was purified by a combination of affinity purification and ion exchange chromatography
  • 製品の状態Liquid
  • 備考ab51403 corresponds to the first 76 aa residues after the signal peptide has been cleved.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • ANFB_HUMAN
    • BNP
    • BNP(1-32)
    • BNP(5-29)
    • BNP-32
    • Brain type natriuretic peptide
    • Gamma brain natriuretic peptide
    • Gamma-brain natriuretic peptide
    • Natriuretic peptide precursor B
    • nppb
    • NT proBNP
    see all
  • 機能Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • 組織特異性Brain and also in atria, but at much lower levels than ANP.
  • 配列類似性Belongs to the natriuretic peptide family.
  • 細胞内局在Secreted.
  • Information by UniProt

Recombinant Human proBNP protein (ab51403) 使用論文

ab51403 has not yet been referenced specifically in any publications.

Product Wall

This protein has a 6 His tag on the N terminus.

To answer your questions:

1) MW = 8.46 kDa (with His-tag: 9.28 kDa)
ab51403 corresponds to the first 76 aa residues after the signal peptide has been cleaved, not the full length unprocessed precursor whose MW is about 15 kDa (http://www....

Read More

Thank you for your reply. There are two amino acids "LE" before the 6x His tag. Please let me know if you need any additional information.

Thank you for your patience. My colleague has confirmed thatthere were amino acids that were added before the His tag for ab51403. I hope this helps, please let me know if you need any additional information or assistance.

Thank you for contacting us. The His tag is at C-terminal end of protein. I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"