Recombinant Human PPP1R3A protein (ab116962)

製品の概要

  • 製品名
    Recombinant Human PPP1R3A protein
  • タンパク質長
    Protein fragment

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      PSEVPSQISKDNFLEVPNLSDSLCEDEEVTFQPGFSPQPSRRGSDSSEDI YLDTPSSGTRRVSFADSFGFNLVSVKEFDCWELPSASTTFDLGTDIFHT
    • 分子量
      37 kDa including tags
    • 領域
      3 to 101

特性

Our Abpromise guarantee covers the use of ab116962 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • Glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle
    • Glycogen associated regulatory subunit of protein phosphatase 1
    • GM
    • PP1G
    • PPP1R3
    • PPP1R3A
    • PPR3A_HUMAN
    • Protein phosphatase 1 glycogen-associated regulatory subunit
    • Protein phosphatase 1 glycogen-targeting subunit, muscle
    • Protein phosphatase 1 regulatory subunit 3A
    • Protein phosphatase 1 regulatory subunit GM
    • protein phosphatase 1, regulatory (inhibitor) subunit 3A
    • Protein phosphatase 1, regulatory subunit 3
    • Protein phosphatase type-1 glycogen targeting subunit
    • RG1
    • Serine /threonine specific protein phosphatase
    • Type 1 protein phosphatase skeletal muscle glycogen targeting subunit
    see all
  • 機能
    Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.
  • 組織特異性
    Skeletal muscle and heart.
  • 関連疾患
    Diabetes mellitus, non-insulin-dependent
  • 配列類似性
    Contains 1 CBM21 (carbohydrate binding type-21) domain.
  • ドメイン
    The CBM21 domain is known to be involved in the localization to glycogen and is characteristic of some regulatory subunit of phosphatase complexes.
  • 翻訳後修飾
    Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase.
  • 細胞内局在
    Membrane.
  • Information by UniProt

Recombinant Human PPP1R3A protein 画像

  • 12.5% SDS-PAGE showing ab116962 at approximately 36.52kDa stained with Coomassie Blue.

Recombinant Human PPP1R3A protein (ab116962) 使用論文

ab116962 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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