Recombinant Human PPP1R3A protein (ab116962)

製品の概要

  • 製品名Recombinant Human PPP1R3A protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号Q16821
    • 生物種Human
    • 配列PSEVPSQISKDNFLEVPNLSDSLCEDEEVTFQPGFSPQPSRRGSDSSEDI YLDTPSSGTRRVSFADSFGFNLVSVKEFDCWELPSASTTFDLGTDIFHT
    • 分子量37 kDa including tags
    • 領域3 to 101

特性

Our Abpromise guarantee covers the use of ab116962 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • Glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle
    • Glycogen associated regulatory subunit of protein phosphatase 1
    • GM
    • PP1G
    • PPP1R3
    • PPP1R3A
    • PPR3A_HUMAN
    • Protein phosphatase 1 glycogen-associated regulatory subunit
    • Protein phosphatase 1 glycogen-targeting subunit, muscle
    • Protein phosphatase 1 regulatory subunit 3A
    • Protein phosphatase 1 regulatory subunit GM
    • protein phosphatase 1, regulatory (inhibitor) subunit 3A
    • Protein phosphatase 1, regulatory subunit 3
    • Protein phosphatase type-1 glycogen targeting subunit
    • RG1
    • Serine /threonine specific protein phosphatase
    • Type 1 protein phosphatase skeletal muscle glycogen targeting subunit
    see all
  • 機能Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.
  • 組織特異性Skeletal muscle and heart.
  • 関連疾患Diabetes mellitus, non-insulin-dependent
  • 配列類似性Contains 1 CBM21 (carbohydrate binding type-21) domain.
  • ドメインThe CBM21 domain is known to be involved in the localization to glycogen and is characteristic of some regulatory subunit of phosphatase complexes.
  • 翻訳後修飾Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase.
  • 細胞内局在Membrane.
  • Information by UniProt

Recombinant Human PPP1R3A protein 画像

  • 12.5% SDS-PAGE showing ab116962 at approximately 36.52kDa stained with Coomassie Blue.

Recombinant Human PPP1R3A protein (ab116962) 使用論文

ab116962 has not yet been referenced specifically in any publications.

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