Recombinant Human PP1C gamma protein (ab114828)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P36873
    • 生物種Human
    • 配列MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQP ILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQS LETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWK TFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGL LCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQV VEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE KKKPNATRPVTPPRGMITKQAKK
    • 分子量61 kDa including tags
    • 領域1 to 323

特性

Our Abpromise guarantee covers the use of ab114828 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • PP 1G
    • PP-1G
    • PP1C
    • PP1G
    • PP1G_HUMAN
    • PP1gamma
    • PPP 1G
    • PPP1CC
    • PPP1G
    • Protein phosphatase 1, catalytic subunit, gamma isozyme
    • Protein phosphatase 1C catalytic subunit
    • Serine/threonine phosphatase 1 gamma
    • Serine/threonine protein phosphatase PP1 gamma catalytic subunit
    • Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
    see all
  • 機能Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
  • 配列類似性Belongs to the PPP phosphatase family. PP-1 subfamily.
  • 細胞内局在Cytoplasm. Nucleus. Nucleus > nucleolus. Nucleus > nucleoplasm. Nucleus speckle. Chromosome > centromere > kinetochore. Cleavage furrow. Midbody. Colocalizes with SPZ1 in the nucleus (By similarity). Rapidly exchanges between the nucleolar, nucleoplasmic and cytoplasmic compartments. Highly mobile in cells and can be relocalized through interaction with targeting subunits. In the presence of PPP1R8 relocalizes from the nucleolus to nuclear speckles. Shows a dynamic targeting to specific sites throughout the cell cycle. Highly concentrated in nucleoli of interphase cells and localizes at kinetochores early in mitosis. Relocalization to chromosome-containing regions occurs at the transition from early to late anaphase. Also accumulates at the cleavage furrow and midbody by telophase.
  • Information by UniProt

Recombinant Human PP1C gamma protein 画像

  • 12.5% SDS-PAGE Stained with Coomassie Blue

Recombinant Human PP1C gamma protein (ab114828) 使用論文

ab114828 has not yet been referenced specifically in any publications.

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