製品の概要

  • 製品名
    Recombinant Human POLR2E protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Human

関連製品

特性

Our Abpromise guarantee covers the use of ab81886 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 95 % SDS-PAGE.

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

関連情報

  • 別名
    • and III subunit ABC1
    • and III subunit RPABC1
    • DNA directed RNA polymerase II 23 kDa polypeptide
    • DNA directed RNA polymerase II polypeptide E
    • DNA directed RNA polymerase II subunit E
    • DNA directed RNA polymerases I II and III subunit RPABC1
    • DNA-directed RNA polymerase II 23 kDa polypeptide
    • DNA-directed RNA polymerase II subunit E
    • DNA-directed RNA polymerases I
    • hRPB25
    • hsRPB5
    • II
    • Polr2e
    • Polymerase (RNA) II (DNA directed) polypeptide E (25kD)
    • Polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
    • RNA polymerases I
    • RNA polymerases I, II, and III subunit ABC1
    • RPAB1_HUMAN
    • RPABC1
    • RPB5
    • RPB5 homolog
    • XAP4
    see all
  • 機能
    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
  • 配列類似性
    Belongs to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family.
  • 細胞内局在
    Nucleus.
  • Information by UniProt

参考文献

ab81886 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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