Recombinant Human Plzf protein (ab125992)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q05516
    • 生物種Human
    • 配列GELAVGMKSESRTIGEQCSVCGVELPDNEAVEQHRKLHSGMKTYGCELCG KRFLDSLRLRMHLLAHSAGAKAFVCDQCGAQFSKEDALETHRQTHTGTDM AVFCLLCGKRFQAQSALQQHMEVHAGVRSYICSECNRTFPSHTALKRHLR SHTGDHPYECEFCGSCFRDESTLKSHKRIHTGEKPYECNGCGKKFSLKHQ LETHYRVHTGEKPFECKLCHQRSRDYSAMIKHLRTHNGASPYQCTICTEY CPSLSSMQKHMKGHKPEEIP
    • 領域389 to 658

特性

Our Abpromise guarantee covers the use of ab125992 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 製品の状態Lyophilised
  • 備考For 50ug package, it is suggested to dissolve directly in 50ul DDW and the final concentration is 1.0ug/ul
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride, 0.2% Guanidine HCl

  • 再構成Reconstitute with water to desired concentration.

関連情報

  • 別名
    • AI467657
    • lu
    • PLZF
    • Promyelocytic leukemia zinc finger protein
    • ZBT16_HUMAN
    • ZBTB16
    • Zfp145
    • Zinc finger and BTB domain containing 16
    • zinc finger and BTB domain containing protein 16
    • Zinc finger and BTB domain-containing protein 16
    • Zinc finger protein 145
    • Zinc finger protein 145 (Kruppel like expressed in promyelocytic leukemia)
    • Zinc finger protein PLZF
    • Znf145
    see all
  • 機能Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  • 組織特異性Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.
  • パスウェイProtein modification; protein ubiquitination.
  • 関連疾患Skeletal defects, genital hypoplasia, and mental retardation
    A chromosomal aberration involving ZBTB16 may be a cause of acute promyelocytic leukemia (APL). Translocation t(11;17)(q32;q21) with RARA.
  • 配列類似性Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 1 BTB (POZ) domain.
    Contains 9 C2H2-type zinc fingers.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human Plzf protein (ab125992) 使用論文

ab125992 has not yet been referenced specifically in any publications.

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