製品の概要

法規制情報

製品の詳細

  • 由来
    Recombinant
  • 由来
    Baculovirus infected Sf9 cells
  • アミノ酸配列
    • 生物種
      Human

特性

Our Abpromise guarantee covers the use of ab89860 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    The specific activity of ab89860 was determined to be 74 nmol/min/mg
  • アプリケーション

    SDS-PAGE

    Western blot

    Functional Studies

  • 製品の状態
    Liquid
  • 備考

    ab204856 (CREB peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • Cardiolipin activated protein kinase Pak2
    • MGC150606
    • MGC71074
    • PAK 2
    • PAK2
    • PKN gamma
    • PKN2
    • PKN2_HUMAN
    • PRK2
    • PRKCL2
    • PRO2042
    • Protein kinase C like 2
    • Protein kinase C related kinase 2
    • Protein kinase C-like 2
    • Protein kinase N2
    • Protein-kinase C-related kinase 2
    • Serine/threonine-protein kinase N2
    see all
  • 機能
    Exhibits a preference for highly basic protein substrates.
  • 配列類似性
    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 C2 domain.
    Contains 1 protein kinase domain.
    Contains 3 REM (Hr1) repeats.
  • ドメイン
    The C1 domain does not bind the diacylglycerol (DAG).
  • 翻訳後修飾
    Autophosphorylated.
    Activated by limited proteolysis with trypsin.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

画像

  • Kinase Assay demonstrating specific activity of ab89860
  • SDS-PAGE showing ab89860 at approximately 145kDa

参考文献

ab89860 has not yet been referenced specifically in any publications.

レビューと Q&A

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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