Recombinant human PI4 kinase beta protein (ab105199)

製品の概要

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Baculovirus infected Sf9 cells
  • アミノ酸配列
    • アクセッション番号Q9UBF8-2
    • 生物種Human
    • 分子量120 kDa including tags
    • 領域1 to 801

関連製品

特性

Our Abpromise guarantee covers the use of ab105199 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性The Specific activity of ab105199 was determined to be 32 nmol/min/mg.
  • アプリケーション

    SDS-PAGE

    Western blot

    Functional Studies

  • 精製度> 90 % SDS-PAGE.
    Purity was determined to be >90% by densitometry.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • DKFZp686O1820
    • FLJ30129
    • NPIK
    • Phosphatidylinositol 4 kinase beta
    • Phosphatidylinositol 4 kinase catalytic beta
    • Phosphatidylinositol 4 kinase catalytic beta polypeptide
    • Phosphatidylinositol 4 kinase wortmannin sensitive
    • Phosphatidylinositol 4-kinase beta
    • PI4K BETA
    • PI4K-beta
    • PI4K92
    • PI4KB
    • PI4KB_HUMAN
    • PI4Kbeta
    • PI4KIIIbeta
    • PIK4CB
    • PtdIns 4 kinase
    • PtdIns 4-kinase beta
    • Type III phosphatidylinositol 4 kinase beta
    see all
  • 機能Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking.
  • 組織特異性Widely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver.
  • 配列類似性Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
    Contains 1 PI3K/PI4K domain.
    Contains 1 PIK helical domain.
  • 細胞内局在Endomembrane system. Mitochondrion outer membrane. Rough endoplasmic reticulum membrane. Golgi apparatus. Cytoplasm, perinuclear region. Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) on the Golgi complex.
  • Information by UniProt

Recombinant human PI4 kinase beta protein 画像

  • The Specific activity of ab105199 was determined to be 32 nmol/min/mg.
  • SDS-PAGE showing ab105199 at approximately 120kDa.

Recombinant human PI4 kinase beta protein (ab105199) 使用論文

ab105199 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab105199.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"