製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P39687
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMEMGRRIHLELRNRTPSDVKELVLDNSRSN EGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSGGL EVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLND YRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYD EDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGE EERGQKRKREPEDEGEDDD
    • 分子量31 kDa including tags
    • 領域1 to 249
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab101155 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab101155 was purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: 0% None
    Constituents: 10% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, 1mM DTT, 0.1mM PMSF, pH 8.0

関連情報

  • 別名
    • acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
    • Acidic leucine-rich nuclear phosphoprotein 32 family member A
    • Acidic nuclear phosphoprotein 32 family member A
    • Acidic nuclear phosphoprotein pp32
    • AN32A_HUMAN
    • ANP32A
    • C15orf1
    • Cerebellar leucine rich acidic nuclear protein
    • Hepatopoietin Cn
    • HPPCn
    • I1PP2A
    • Inhibitor 1 of protein phosphatase 2A
    • inhibitor-1 of protein phosphatase-2A
    • Lanp
    • Leucine rich acidic nuclear protein
    • Leucine-rich acidic nuclear protein
    • MAPM
    • Mapmodulin
    • MGC119787
    • MGC150373
    • PHAPI
    • Potent heat stable protein phosphatase 2A inhibitor I1PP2A
    • Potent heat-stable protein phosphatase 2A inhibitor I1PP2A
    • PP32
    • Putative HLA DR associated protein I
    • Putative HLA-DR-associated protein I
    • Putative human HLA class II associated protein I
    • Putative human HLA class II-associated protein
    see all
  • 機能Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.
  • 組織特異性Expressed in all tissues tested. Highly expressed in kidney and skeletal muscle, moderate levels of expression in brain, placenta and pancreas, and weakly expressed in lung. Found in all regions of the brain examined (amygdala, caudate nucleus, corpus callosum, hippocampus and thalamus), with highest levels in amygdala.
  • 配列類似性Belongs to the ANP32 family.
    Contains 4 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
  • 翻訳後修飾Phosphorylated on serine residues.
    The N-terminus is blocked.
    Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group.
  • 細胞内局在Nucleus. Cytoplasm. Endoplasmic reticulum. Translocates to the cytoplasm during the process of neuritogenesis (By similarity). Shuttles between nucleus and cytoplasm.
  • Information by UniProt

Recombinant Human PHAP1 protein 画像

  • 15% SDS-PAGE (3 µg)

Recombinant Human PHAP1 protein (ab101155) 使用論文

ab101155 has not yet been referenced specifically in any publications.

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