Recombinant human PDP2 protein (ab110358)

製品の概要

  • 製品名
    Recombinant human PDP2 protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 領域
      67 to 529
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab110358 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Sandwich ELISA

    Functional Studies

  • 精製度
    > 90 % Purified via His tag.

  • 製品の状態
    Liquid
  • 備考

    PDH Kinases (PDKs) deactivate PDH by reversible phosphorylation. In humans and rodents, 4 PDK's are present in an organ-dependent manner. In all cases, PDK's are physically part of the PDH complex (binding via lipoyl domain 2 of E2), and they phosphorylate the E1 subunit at 3 specific serine residues. PDH phosphatases remove the phosphorylation and restore activity of PDH.

    Product was previously marketed under the MitoSciences sub-brand.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.14% Sodium phosphate, 1.46% Sodium chloride, 30% Glycerol, 0.08% DTT, 0.02% EDTA, 0.05% Triton-X-100

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2
    • KIAA1348
    • mitochondrial
    • PDP 2
    • Pdp2
    • PDP2_HUMAN
    • PDPC 2
    • PPM2B
    • PPM2C2
    • Protein phosphatase 2C magnesium dependent catalytic subunit 2
    • Protein phosphatase Mg2+/Mn2+ dependent 2B
    • Pyruvate dehydrogenase phosphatase 2
    • Pyruvate dehydrogenase phosphatase catalytic subunit 2
    • pyruvate dehydrogenase phosphatase isoenzyme 2
    • Pyruvate dehydrogenase phosphatase, catalytic subunit 2
    see all
  • 機能
    Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
  • 配列類似性
    Belongs to the PP2C family.
  • 細胞内局在
    Mitochondrion matrix.
  • Information by UniProt

Recombinant human PDP2 protein (ab110358) 使用論文

ab110358 has not yet been referenced specifically in any publications.

Product Wall

We advise use of PBS for homogenization of muscle tissue. We have not tested the use of this kit with fat tissue. If you have a favorite homogenization buffer, we would advice to prepare the homogenates of both tissues in both buffers in parallel , run...

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Thank you for your enquiry.

I can confirm that these proteins have been used in functional assays in the following publications using Pyruvate-dehydrogenase-PDH-Enzyme-Activity-Microplate-Assay-Kit-ab109902:

http://www.abcam.com/i...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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