製品の概要

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Baculovirus
  • アミノ酸配列
    • アクセッション番号Q9NP56
    • 生物種Human
    • 分子量73 kDa including tags
    • 領域1 to 450

特性

Our Abpromise guarantee covers the use of ab101593 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性The specific activity of PDE7B is determined to be 28 nmol/min/mg.
  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 精製度> 80 % SDS-PAGE.
    The purity was determined to be >80% by densitometry
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • bA472E5.1
    • cAMP specific 3 5 cyclic phosphodiesterase 7B
    • cAMP specific 3'5' cyclic phosphodiesterase 7B
    • High affinity cAMP specific 3 5 cyclic phosphodiesterase
    • High affinity cAMP specific 3'5' cyclic phosphodiesterase
    • MGC88256
    • OTTHUMP00000017267
    • PDE 7B
    • PDE7B protein
    • Phosphodiesterase 7B
    • Phosphodiesterase7B
    • RNPDE7B
    • Rolipram insensitive phosphodiesterase type 7
    see all
  • 関連性PDE7B is a cAMP specific phosphodiesterase. The cAMP-specific phosphodiesterase type-7 (PDE7) family is comprised of 2 genes (PDE7A and PDE7B) each with multiple splice variants generated by RNA splicing and use of alternate initiation sites. PDE7B has three splice variants (PDE7B1 = 446 amino acid; PDE7B2 =359 amino acids and PDE7B3 = 459 amino acids. Both PDE7B2 ad PDE7B3 posses unique N-terminal sequences. PDE7B is expressed in various tissues including skeletal muscle, heart, lung and testis. PDE7B may be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.
  • 細胞内局在cytosol

Recombinant human PDE7B protein 画像

  • SDS-PAGE analysis of ab101593
  • Specific activity of ab101593

Recombinant human PDE7B protein (ab101593) 使用論文

ab101593 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab101593.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"