製品の概要

  • 製品名Recombinant Human PDCD6 protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号O75340
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMAAYSYRPGPGAGPGPAAGAALPDQSFLWN VFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGV NFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQF HDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSY EQYLSMVFSIV
    • 分子量24 kDa including tags
    • 領域1 to 191
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab104605 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 95 % SDS-PAGE.
    ab104605 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 40% Glycerol, 10mM Sodium citrate, pH 3.5

関連情報

  • 別名
    • AIP1
    • ALG 2
    • ALG-2-interacting protein 1
    • ALG2
    • ALIX
    • Apoptosis linked gene 2
    • Apoptosis linked gene 2 protein
    • Apoptosis-linked gene 2 protein
    • FLJ42309
    • FLJ46208
    • Hp95
    • KIAA1375
    • MA 3
    • MA3
    • MGC111017
    • MGC119050
    • MGC9123
    • PDCD 6
    • Pdcd6
    • PDCD6_HUMAN
    • PEF 1B
    • PEF1B
    • Probable calcium binding protein ALG 2
    • Probable calcium binding protein ALG2
    • Probable calcium-binding protein ALG-2
    • Programmed cell death 6
    • Programmed cell death 6-interacting protein
    • Programmed cell death protein 6
    • PS 2
    • PS2
    see all
  • 機能Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)-regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis; the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca(2+) affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.
  • 配列類似性Contains 5 EF-hand domains.
  • 細胞内局在Nucleus membrane. Endoplasmic reticulum membrane. Nucleus. Endosome. Interaction with RBM22 induces relocalization from the cytoplasm to the nucleus. Translocated from the cytoplasm to the nucleus after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules.
  • Information by UniProt

Recombinant Human PDCD6 protein 画像

  • 15% SDS-PAGE showing ab104605 (3 µg) at approximately 24 kDa.

Recombinant Human PDCD6 protein (ab104605) 使用論文

ab104605 has not yet been referenced specifically in any publications.

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