Recombinant Human PCBP2/hnRNP E2 protein (ab116820)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINIS EGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTL RLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG IPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGS DSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQS HFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINV RLSSETGGMGSS
    • 分子量
      66 kDa including tags
    • 領域
      1 to 365

特性

Our Abpromise guarantee covers the use of ab116820 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

関連情報

  • 別名
    • Alpha CP2
    • Alpha-CP2
    • alphaCP-2
    • Cbp
    • CTBP
    • Heterogeneous nuclear ribonucleoprotein E2
    • Heterogenous nuclear ribonucleoprotein E2
    • hnRNP E2
    • hnRNP-E2
    • HNRNPE2
    • Hnrnpx
    • HNRPE2
    • Hnrpx
    • MGC110998
    • PCBP2
    • PCBP2_HUMAN
    • poly(rC) binding protein 2
    • Poly(rC)-binding protein 2
    • Putative heterogeneous nuclear ribonucleoprotein X
    • rCbinding protein 2
    see all
  • 機能
    Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation.
  • 組織特異性
    Detected in all tissues examined.
  • 配列類似性
    Contains 3 KH domains.
  • 翻訳後修飾
    Phosphorylated. The non-phosphorylated form(s) exhibited the strongest poly(rC)-binding activity.
  • 細胞内局在
    Nucleus. Cytoplasm. Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm.
  • Information by UniProt

Recombinant Human PCBP2/hnRNP E2 protein 画像

  • 12.5% SDS-PAGE showing ab116820 at approximately 65.93kDa.
    Stained with Coomassie Blue.

Recombinant Human PCBP2/hnRNP E2 protein (ab116820) 使用論文

ab116820 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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