製品の概要

  • 製品名
    Recombinant Human PCBD1 protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHH SSGLVPRGSH MAGKAHRLSA EERDQLLPNL RAVGWNELEG RDAIFKQFHF KDFNRAFGFM TRVALQAEKL DHHPEWFNVY NKVHITLSTH ECAGLSERDI NLASFIEQVA VSMT
    • 分子量
      14 kDa including tags
    • 領域
      1 to 104
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab100942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Mass Spectrometry

    SDS-PAGE

  • 質量分析
    MALDI-TOF
  • 精製度
    > 95 % SDS-PAGE.
    ab100942 was purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8

関連情報

  • 別名
    • 4 alpha hydroxy tetrahydropterin dehydratase
    • 4-alpha-hydroxy-tetrahydropterin dehydratase
    • 6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
    • 6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)
    • DCoH
    • Dimerization cofactor of hepatic nuclear factor 1 alpha
    • Dimerization cofactor of hepatocyte nuclear factor 1 alpha
    • Dimerization cofactor of hepatocyte nuclear factor 1-alpha
    • Dimerization cofactor of HNF1
    • Dimerizing cofactor for HNF1
    • PCBD
    • PCBD 1
    • PCBD1
    • PCD
    • Phenylalanine hydroxylase stimulating protein
    • Phenylalanine hydroxylase-stimulating protein
    • PHS
    • PHS_HUMAN
    • Pterin 4 alpha carbinolamine dehydratase
    • Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
    • Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)
    • Pterin carbinolamine dehydratase
    • Pterin-4-alpha-carbinolamine dehydratase
    see all
  • 機能
    Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity.
  • 関連疾患
    Defects in PCBD1 are the cause of BH4-deficient hyperphenylalaninemia type D (HPABH4D) [MIM:264070]; also known as hyperphenylalaninemia with primapterinuria. HPABH4D is characterized by the excretion of 7-substituted pterins in the urine of affected patients.
  • 配列類似性
    Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
  • 細胞内局在
    Cytoplasm. Nucleus. Cytoplasmic and/or nuclear.
  • Information by UniProt

Recombinant Human PCBD1 protein 画像

  • ab100942, at 3 µg, on 15% SDS PAGE.

Recombinant Human PCBD1 protein (ab100942) 使用論文

ab100942 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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