製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human

特性

Our Abpromise guarantee covers the use of ab82048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Functional Studies

    SDS-PAGE

    EMSA

  • 精製度> 95 % SDS-PAGE.
    ab82048 is purified by conventional chromatography and contains no detectable protease, DNase and RNase activity.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

関連情報

  • 別名
    • Activated RNA polymerase II transcriptional coactivator p15
    • Interferon related developmental regulator 1
    • MGC102747
    • p14
    • P15
    • PC4
    • PC4 LSB
    • Positive cofactor 4
    • RPO2TC1
    • Sub1
    • SUB1 homolog
    • TCP4_HUMAN
    see all
  • 機能General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
  • 配列類似性Belongs to the transcriptional coactivator PC4 family.
  • 翻訳後修飾Activity is controlled by protein kinases that target the regulatory region. Phosphorylation inactivates both ds DNA-binding and cofactor function, but does not affect binding to ssDNA. Seems to be phosphorylated in vivo by CK2 in at least 7 sites in the N-terminal Ser-rich region.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human PC4 protein (ab82048) 使用論文

ab82048 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab82048.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"