製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P23759
    • 生物種Human
    • 配列GGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGY QYGQYGQSECLVPWASPVPIPSPTPRASCLFMESYKVVSGWGMSISQMEK LKSSQMEQFT
    • 分子量38 kDa including tags
    • 領域411 to 521

特性

Our Abpromise guarantee covers the use of ab114237 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • FLJ37460
    • HUP1
    • OTTHUMP00000002534
    • Paired box 7
    • Paired box gene 7
    • Paired box homeotic gene 7
    • Paired box protein Pax-7
    • Paired domain gene 7
    • Paired domain gene HuP1
    • Pax7
    • PAX7 transcriptional factor
    • PAX7/FKHR fusion gene, included
    • PAX7_HUMAN
    • PAX7B
    • RGD1564360
    • RMS2
    see all
  • 機能Probable transcription factor. May have a role in myogenesis.
  • 関連疾患Defects in PAX7 are a cause of rhabdomyosarcoma type 2 (RMS2) [MIM:268220]. It is a form of rhabdomyosarcoma, a highly malignant tumor of striated muscle derived from primitive mesenchimal cells and exhibiting differentiation along rhabdomyoblastic lines. Rhabdomyosarcoma is one of the most frequently occurring soft tissue sarcomas and the most common in children. It occurs in four forms: alveolar, pleomorphic, embryonal and botryoidal rhabdomyosarcomas. Note=A chromosomal aberration involving PAX7 is found in rhabdomyosarcoma. Translocation t(1;13)(p36;q14) with FOXO1. The resulting protein is a transcriptional activator.
  • 配列類似性Belongs to the paired homeobox family.
    Contains 1 homeobox DNA-binding domain.
    Contains 1 paired domain.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human PAX7 protein 画像

  • 12.5% SDS-PAGE showing ab114237 at approximately 38.21kDa stained with Coomassie Blue.

Recombinant Human PAX7 protein (ab114237) 使用論文

ab114237 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"