Recombinant Human PAPSS1 protein (ab123177)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号O43252
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MGSHMRATNV TYQAHHVSRN KRGQVVGTRG GFRGCTVWLT GLSGAGKTTV SMALEEYLVC HGIPCYTLDG DNIRQGLNKN LGFSPEDREE NVRRIAEVAK LFADAGLVCI TSFISPYTQD RNNARQIHEG ASLPFFEVFV DAPLHVCEQR DVKGLYKKAR AGEIKGFTGI DSEYEKPEAP ELVLKTDSCD VNDCVQQVVE LLQERDIVPV DASYEVKELY VPENKLHLAK TDAETLPALK INKVDMQWVQ VLAEGWATPL NGFMREREYL QCLHFDCLLD GGVINLSVPI VLTATHEDKE RLDGCTAFAL MYEGRRVAIL RNPEFFEHRK EERCARQWGT TCKNHPYIKM VMEQGDWLIG GDLQVLDRVY WNDGLDQYRL TPTELKQKFK DMNADAVFAF QLRNPVHNGH ALLMQDTHKQ LLERGYRRPV LLLHPLGGWT KDDDVPLMWR MKQHAAVLEE GVLNPETTVV AIFPSPMMYA GPTEVQWHCR ARMVAGANFY IVGRDPAGMP HPETGKDLYE PSHGAKVLTM APGLITLEIV PFRVAAYNKK KKRMDYYDSE HHEDFEFISG TRMRKLAREG QKPPEGFMAP KAWTVLTEYY KSLEKA
    • 分子量71 kDa including tags
    • 領域24 to 624
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab123177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 85 % SDS-PAGE.
    ab123177 is purified using conventional chromatography.
  • 製品の状態Liquid
  • 備考Additional E.C. Number: =2.7.7.4
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

関連情報

  • 別名
    • 3 prime phosphoadenosine 5 prime phosphosulfate synthase 1
    • 3' phosphoadenosine 5' phosphosulfate synthase 1
    • 3''-phosphoadenosine-5''-phosphosulfate synthase
    • Adenosine-5''-phosphosulfate 3''-phosphotransferase
    • Adenylyl-sulfate kinase
    • Adenylylsulfate 3''-phosphotransferase
    • APS kinase
    • ATP-sulfurylase
    • ATPSK 1
    • ATPSK1
    • ATPSK2
    • Bifunctional 3' phosphoadenosine 5' phosphosulfate synthetase 1
    • PAPS synthase 1
    • PAPS synthetase 1
    • PAPS1_HUMAN
    • PAPSS
    • PAPSS 1
    • PAPSS1
    • SAT
    • SK 1
    • SK1
    • SK2
    • Sulfate adenylate transferase
    • Sulfurylase kinase 1
    see all
  • 機能Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. Also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.
  • 組織特異性Expressed in testis, pancreas, kidney, thymus, prostate, ovary, small intestine, colon, leukocytes and liver. Also expressed in high endothelial venules (HEV) cells and in cartilage.
  • パスウェイSulfur metabolism; sulfate assimilation.
  • 配列類似性In the N-terminal section; belongs to the APS kinase family.
    In the C-terminal section; belongs to the sulfate adenylyltransferase family.
  • Information by UniProt

Recombinant Human PAPSS1 protein 画像

  • 15% SDS-PAGE analysis of ab123177 (3ug)

Recombinant Human PAPSS1 protein (ab123177) 使用論文

ab123177 has not yet been referenced specifically in any publications.

Product Wall


The lab let me know that the protein’s biological activity hasn’t been tested yet.
But the protein hasn’t been exposed to denaturing agents, so it is possible that it’s bioactive.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"