製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P19021
    • 生物種Human
    • 配列FRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMY LMMSVDTVIPAGEKVVNSDISCHYKNYPMHVFAYRVHTHHLGKVVSGYRV RNGQWTLI
    • 分子量38 kDa including tags
    • 領域151 to 258

特性

Our Abpromise guarantee covers the use of ab116776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

    ELISA

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • AMD_HUMAN
    • PAL
    • PAM
    • Pancreatic peptidylglycine alpha amidating monooxygenase
    • Peptidyl alpha amidating enzyme
    • Peptidyl alpha hydroxyglycine alpha amidating lyase
    • Peptidyl-alpha-hydroxyglycine alpha-amidating lyase
    • Peptidylamidoglycolate lyase
    • Peptidylglycine 2 hydroxylase
    • Peptidylglycine alpha amidating monooxygenase
    • Peptidylglycine alpha hydroxylating monooxygenase
    • PHM
    see all
  • 機能Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.
  • 配列類似性In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
    In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
    Contains 5 NHL repeats.
  • 細胞内局在Membrane and Secreted. Secreted from secretory granules.
  • Information by UniProt

Recombinant Human PAM protein 画像

  • 12.5% SDS-PAGE showing ab116776 at approximately 37.51kDa.
    Stained with Coomassie Blue.

Recombinant Human PAM protein (ab116776) 使用論文

ab116776 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"