Recombinant Human p18 INK4c protein (ab119460)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P42773
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMAEPWGNELASAAARGDLEQLTSLLQNNVN VNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARA GFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV GHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ
    • 分子量21 kDa including tags
    • 領域1 to 168
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab119460 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Mass Spectrometry

    SDS-PAGE

  • 質量分析
    MALDI-TOF
  • 精製度> 95 % SDS-PAGE.
    ab119460 was purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.03% DTT, 10% Glycerol, 1.17% Sodium chloride

関連情報

  • 別名
    • CDK6 inhibitor p18
    • CDKN 2C
    • CDKN 6
    • Cdkn2c
    • CDKN6
    • CDN2C_HUMAN
    • Cyclin dependent inhibitor
    • Cyclin dependent kinase 4 inhibitor C
    • Cyclin dependent kinase 6 inhibitor
    • Cyclin dependent kinase 6 inhibitor p18
    • Cyclin dependent kinase inhibitor 2C
    • Cyclin dependent kinase inhibitor 2C (p18 inhibits CDK4)
    • Cyclin-dependent kinase 4 inhibitor C
    • Cyclin-dependent kinase 6 inhibitor
    • INK4C
    • OTTHUMP00000046546
    • p18
    • p18 inhibits CDK4
    • p18 INK4c
    • p18 INK6
    • p18-INK4c
    • p18-INK6
    see all
  • 機能Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
  • 組織特異性Highest levels found in skeletal muscle. Also found in pancreas and heart.
  • 配列類似性Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
    Contains 4 ANK repeats.
  • Information by UniProt

Recombinant Human p18 INK4c protein 画像

  • 15% SDS-PAGE showing ab119460 at approximately 20.7kDa (3µg).

Recombinant Human p18 INK4c protein (ab119460) 使用論文

ab119460 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab119460.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"